Like humans, various animal can have diseases that will significantly impact the population. In the case of the Black-Footed Ferret, which is already struggling with a lack of genetic diversity and general population size, sylvatic plague, which is not unlike bubonic plague, can have devastating effects. Trying to vaccinate the population individually has been tricky, and would require constant upkeep. However, through the use of CRISPR it would be possible to “encod[e] antibodies generated by vaccination and  them into the ferrets’ DNA” (Specter 4). This would also ensure that future generations of ferrets would be free from the disease. It has also been suggested that a similar technique could be used on white-footed mice and Lyme disease, but concerns have been raised about the possibility of doing this kind of editing could have unforeseen consequences, and caution should be used. Given the prevalence of these mice, the effect they currently have on their ecosystem, and how untested with this type of work is, going through with this type of project without someway to reverse it would be risky and irresponsible. (Specter 4).
In terms of human, It does seem like too big a risk to edit the entire next generations genes for any particular disease given we don’t know enough to even feel comfortable testing it on animals. Far more testing should be done before it’s attempted on any humans in any form. However, the screening of parents for diseases they could pass on, and of embryos for the diseases they already carry are actions which can save countless children from diseases that are horrible to live with and are far smaller in scale than editing a vaccine into the entire populations DNA.